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Rigaku Selected As Equipment Provider for UK National Crystallography Service
Feb 04, 2011
THE WOODLANDS, TEXAS -- Rigaku Americas Corporation is pleased to announce that the UK National Crystallography Service (NCS) has chosen to Rigaku as the primary vendor for a major upgrade of their single crystal X-ray diffraction facilities at the Chemical Crystallography Laboratory within the School of Chemistry, University of Southampton. The update includes both chemical (small molecule) and macromolecular X-ray crystallographic instrumentation as well as crystallization automation tools. When the new instrumentation is installed, the NCS will be the best equipped chemical crystallography lab in the world.
For small molecule (chemical) X-ray crystallography, the laboratory selected a Rigaku Saturn Kappa CCD crystallography system based around a dual-port, Mo-anode Rigaku FR-E+ SuperBright microfocus rotating anode X-ray source, where each port is equipped with a Kappa goniometer and Rigaku Saturn 724HG 18-bit CCD detector. The Rigaku FR-E+ SuperBright is the most intense home laboratory X-ray source available today for small molecule crystallography, providing brightness exceeding some second generation bending magnet synchrotron beamlines. The differences in port performance are achieved by differential optics selection, with one port employing a very high flux VariMax VHF optic while the other VariMax HF optic delivers low divergence.
For analyzing absolute configuration, extremely small crystals, as well as structural biology, NCS chose to purchase a Rigaku HighFlux HomeLab™ system equipped with the industry standard Rigaku MicroMax 007HF microfocus rotating anode X-ray generator (Cu-anode) fitted with a VariMax HF optic, a 4-axis partial χ goniometer and the large aperture Rigaku Saturn 944HG 18-bit CCD detector. In addition, the lab acquired an Art Robbins Gryphon for setting up crystallization plates and a Rigaku Desktop Alchemist to make customized crystallization screens.
Commenting on the purchase, Prof. Phil Gale, Head of Service and the School of Chemistry commented that, "I'm delighted that the NCS will be working in partnership with Rigaku to develop the cutting edge of both small molecule and macromolecular crystallography. The facility in Southampton will be an internationally leading centre and will remain at the forefront of structural science over the coming years." Reinforcing this sentiment, NCS Director Dr Simon Coles elaborated that, "This collaboration with Rigaku puts us in a world leading position. The sheer power of the FRE+ impressed me greatly and this, coupled with state-of-the-art optics and the new improved sensitivity Saturn CCD detector, gave us the confidence to enter into this partnership. Rigaku have an excellent reputation for collaboration and building bespoke facilities and we believe this strength will help us achieve the cutting edge position that we need to be in."
The National Service for X-ray crystallography, founded in 1981 at QMC London by Mike Hursthouse, has been in continuous operation for 30 years. In 1997 the service was revamped and moved to its new home at the University of Southampton. Throughout its existence, the National Service has continued to demonstrate demand from, and provide facilities for, the chemistry, materials and crystallography communities, whilst promoting the technique and innovation.
Since its inception in Japan in 1951, Rigaku has been at the forefront of analytical and industrial instrumentation technology. Rigaku and its subsidiaries form a global group focused on life sciences and general purpose analytical instrumentation. With hundreds of major innovations to its credit, Rigaku and its subsidiary companies are world leaders in the fields of small molecule and protein crystallography, X-ray spectrometry and diffraction, X-ray optics, as well as semiconductor metrology. Rigaku employs over 1,100 people in the manufacture and support of its analytical equipment. Its products are in use in more than 70 countries - supporting research, development, and quality assurance activities. Throughout the world, Rigaku continuously promotes partnerships, dialog, and innovation within the global scientific and industrial community.
For further information, contact:
Paul N. Swepston, Ph.D.
President, Life Sciences
Rigaku Americas Corporation
Keywords: crystallography,x-ray diffraction,research,england,small molecule Science » Biotechnology
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